I think this is a really tricky issue. For example, love can be considered to be immaterial and it can evidently affect material things through the actions of those in love. But then I'd argue that love is a signal riding on a material medium (the neural nets within our brains). I have often stated that wherever we look we find software to be supervenient on hardware. I am unaware of any evidence for pure Information that exists without a supporting material structure anywhere in the cosmos.Harvey1 wrote: Newtonian mechanics is an approximation to quantum mechanics. It's possible that the uncertainty principle can be more generalized with some yet undiscovered theory, however the uncertainty principle is a theorem in the theory of operators, a derivation of the Cramer-Rao inequality, derivation of the Fourier transform on general locally compact groups, formulation for Fourier integral operators on manifolds, along with other deep mathematical concepts. So, I would argue that the uncertainty principle points to some kind of platonic structure that has deep mathematical significance. Given its importance in explaining the virtual particles, Casimir effect, Hawking radiation, etc., I think we have good reason to believe that the immaterial affects the material.
The question I wish to put here is how are we to know for sure that a platonic view is justified when all we might be doing is to default to this assumption simply because we lack a complete understanding of some phenomenon or other that we are studying. It seems to me that while Physics lacks a Grand Unification Theory we do not know if the laws we are observing represent restrictions of degrees of freedom imposed by some as yet undiscovered, underlying, material framework. The analogy that I like to use is the tracing-out of the image of a penny coin beneath a sheet of paper by rubbing over it with a pencil. If we never saw behind the paper, the impression might seem to comes to us from nowhere.
This topic covers the related issue of prescriptive vs descriptive laws and can serve to host debates that frequently go off-topic in other threads.